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| Dr. Bayan Al-Dabbagh | | | Medical Research Specialist - 1 | | Department of Internal Medicine | | | Phone: | 971 3 7137 623 | | Fax: | 971 3 7672995 | | Email: | bayan.al-dabbagh@uaeu.ac.ae |
College of Medicine and Health Sciences
United Arab Emirates University
P.O.Box 17666, Al-Ain
United Arab Emirates |
| Degree | University | Year |
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| PhD in Biochemistry (Highly Honorable with Praises) | Université Paris-Sud 11 , Orsay, France | 2008 | | DELF A6 (Diplôme d’Etudes en Langue Française) | CAREL , Royan, France | 2004 | | MSc in Applied Molecular Microbiology | University of Nottingham , Nottingham, UK | 2002 | | BSc in Biological Sciences | University of Jordan, Amman, Jordan | 1998 |
| | Appointment | Year |
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| Medical Research Specialist I, FMHS, UAE University | Feb 2010 - Present | | Post Doctoral Research Fellow, Université Paris-Sud 11, France | Sept 2008 - Jan 2010 |
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| Research Interest |
| Diabetes, Obesity, Protein purification and characterization, Bacterial inhibitors. |
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| Selected Publications |
| Alkaabi J, Al-Dabbagh B, Ahmad S, Saadi H, Gariballa S, Al Ghazali M. Glycemic indices of five varieties of dates in healthy and diabetic subjects. Nutrition Journal. 2011; May 28;10:59. |
| Tanino T, Ichikawa S, Al-Dabbagh B, Bouhss A, Oyama H, Matsuda A. Synthesis and biological evaluation of muraymycin analogues active against anti-drug-resistant bacteria. ACS Medicinal Chemistry Letters. 2010; 1(6), 258-262. |
| Lecerclé D, Clouet A, Al-Dabbagh B, Crouvoisier M, Bouhss A, Gravier-Pelletier C, Le Merrer Y. Bacterial transferase MraY inhibitors: synthesis and biological evaluation. Bioorganic & Medicinal Chemistry. 2010; 18(12):4560-4569. |
| Mravljak J, Monasson O, Al-Dabbagh B, Crouvoisier M, Bouhss A, Gravier-Pelletier C, Le Merrer Y. Synthesis and biological evaluation of a diazepanone-based library of liposidomycins analogs as MraY inhibitors. European Journal of Medicinal Chemistry. 2011; 46(5), 1582-1592.
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Al-Dabbagh B, Henry X, El Ghachi M, Auger G, Blanot D, Parquet C, Mengin-Lecreulx D, Bouhss A. Active site mapping of MraY, a member of the polyprenyl-phosphate N-acetylhexosamine 1-phosphate transferase superfamily, catalyzing the first membrane step of peptidoglycan biosynthesis. Biochemistry. 2008; 47(34): 8919-8928.
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| Clouet A, Gravier-Pelletier C, Al-Dabbagh B, Bouhss A, Le Merrer Y. Efficient synthesis of a bacterial translocase MraY inhibitor. Tetrahedron: Asymmetry. 2008; 19(4): 397-400. |
| Alfazari A, Al-Dabbagh B, Almarzooqi S, Albawardi A, Souid A. A Preparation of Murine Liver Fragments for In Vitro Studies. BMC Research Notes. 2013 Feb 25;6(1):70 |
| Alfazari AS, Al-Dabbagh B, Almarzooqi S, Albawardi A, Souid AK. Bioenergetic study of murine hepatic tissue treated in vitro with atorvastatin. BMC Pharmacology and Toxicology. 2013 Feb 28;14(1):15. |
| Tanino T, Al-Dabbagh B, Mengin-Lecreulx D, Bouhss A, Oyama H, Ichikawa S, Matsuda A. Mechanistic analysis of muraymycin analogues: a guide to the design of MraY inhibitors. Journal of Medicinal Chemistry. 2011; 54(24), 8421–8439. |
| Auberger N, Frlan R, Al-Dabbagh B, Bouhss A, Crouvoisier M, Gravier-Pelletier C, Le Merrer Y. Synthesis and biological evaluation of potential new inhibitors of the bacterial transferase MraY with a β-ketophosphonate structure. Organic & Biomolecular Chemistry. 2011; 9(24), 8301-8312. |
| Ii K, Ichikawa S, Al-Dabbagh B, Bouhss A, Matsuda A. Function-oriented synthesis of simplified caprazamycins: discovery of oxazolidine-containing uridine derivatives as antibacterial agents against drug-resistant bacteria. Journal of Medicinal Chemistry. 2010; 53(9):3793-3813. |
Saadi H, Al-Kaabi J, Benbarka M, Khalili A, Mahmeed W, Nagelkerke N, Salustri A, Abdelwarth L, Al Essa A, Yasin J, Al-Dabbagh B, Kazam E. Screening for undiagnosed diabetes and quality of diabetes care in patients followed at primary and tertiary clinics in Abu Dhabi, United Arab Emirates. The Review of Diabetic Studies. 2010; 7(4):293-302.
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| Bouhss A, Al-Dabbagh B, Vincent M, Odaert B, Aumont-Nicaise M, Bressolier P, Desmadril M, Mengin-Lecreulx D, Urdaci M, Gallay J. Specific interactions of clausin, a new lantibiotic, with lipid precursors of the bacterial cell wall. Biophysical Journal. 2009; 97(5): 1390-1397. |
| Al-Dabbagh B, Blanot D, Mengin-lecreulx D, Bouhss A. Preparative enzymatic synthesis of polyprenyl-pyrophosphoryl-N-acetylglucosamine, an essential lipid intermediate for the biosynthesis of various bacterial cell envelope polymers. Analytical Biochemistry. 2009; 391(2): 163-165. |
| Al-Dabbagh B, Mengin-Lecreulx D, Bouhss A. Purification and characterization of the bacterial UDP-GlcNAc: undecaprenyl-phosphate GlcNAc-1-phosphate transferase WecA. Journal of Bacteriology. 2008; 190(21): 7141-7146. |
| Shehab A, Al-Dabbagh B, Almahmeed W, Bustani N, Nagelkerke N, Alnaeemi A, Alsheikh-Ali AA. Prevalence, Characteristics, and In-Hospital Outcomes of Metabolic Syndrome among Patients with Acute Coronary Syndrome in the United Arab Emirates.The Open Cardiovascular Medicine Journal. 2012; 6, 81-87. |
| Shehab A, Al-Dabbagh B, Almahmeed W, Bustani N, Agrawal A, Yusufali AH, Wassef A, Alnaeemi A, Alsheikh-Ali AA. Characteristics, management, and in-hospital outcomes of diabetic patients with acute coronary syndrome in the United Arab Emirates. The Scientific World Journal. 2012; 698597. |
| Shehab A, Yasin J, Hashim MJ, Al-Dabbagh B, Al Mahmeed W, Bustani N, Agrawal A, Yusufali A, Wassef A, Alnaeemi A. Gender differences in acute coronary syndrome in Arab Emirati women – implications for clinical management. Angiology. 2013; 64(1):9-14. |
| Shehab A, Al-Dabbagh B, AlHabib KF, Alsheikh-Ali AA, Almahmeed W, Sulaiman K, Al-Motarreb A, Nagelkerke N, Al Suwaidi J, Hersi A, Al Faleh H, Asaad N, Al Saif S, Amin H. Gender Disparities in the Presentation Management, and Outcomes of Middle Eastern Patients with Acute Coronary Syndrome in GULF RACE-2. Plos One. 2013; 8(2): e55508. doi: 10.1371/journal.pone.0055508. |
| Shehab A, Al-Dabbagh B, Almahmeed W, Bustani N, Nagelkerke N, Agrawal A, Yusufali AH, Wassef A, Alsheikh-Ali AA. Clinical Characteristics, Prevalence, and In-Hospital Outcomes of Heart Failure among Acute Coronary Syndrome Patients in the United Arab Emirates. BMC Research Notes. 2012; 5(1), 534. |
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