Mr. Allen Shahin
Medical Research Specialist - 1
Department of Microbiology and Immunology
Phone: 971 3 7137 645
Fax: 971 3 7671966
Email: shahin.a@uaeu.ac.ae


College of Medicine and Health Sciences

United Arab Emirates University
P.O.Box 17666, Al-Ain
United Arab Emirates
Selected Publications
PAM3CSk4 enhanced beta cell loss and diabetogenisis: the roles of IFN-gamma and IL-17Al-Shamsi M., Shahin A., Iwakura Y., Lukic M., Mensa0Brown E. Clinical Immunology. 2013 October,149,issue 1, pages 86-96 
Derangements of liver tissue bioenergetics in Concanavalin A-induced hepatitis. Al-Shamsi M, Shahin A, Mensah-Brown EP, Souid AK. BMC Gastroenterol. 2013 Jan 12;13:6.  
IFN-γ deficiency exacerbates experimental autoimmune neuritis in mice despite a mitigated systemic Th1 immune response. Zhang HL, Azimullah S, Zheng XY, Wang XK, Amir N, Mensah-Brown EP, Al Shamsi M, Shahin A, Press R, Zhu J, Adem A. J Neuroimmunol. 2012 May 15;246(1-2):18-26  
Protein phosphatase 1-dependent dephosphorylation of Akt is the prime signaling event in sphingosine-induced apoptosis in Jurkat cells. Thayyullathil F, Chathoth S, Shahin A, Kizhakkayil J, Hago A, Patel M, Galadari S. J Cell Biochem. 2011 Apr;112(4):1138-53  
Early influx of macrophages determines susceptibility to experimental allergic encephalomyelitis in Dark Agouti (DA) rats. Mensah-Brown EP, Shahin A, Al Shamisi M, Lukic ML. J Neuroimmunol. 2011 Mar;232(1-2):68-74  
UVC-induced apoptosis in Dubca cells is independent of JNK activation and p53(Ser-15) phosphorylation. Chathoth S, Thayyullathil F, Hago A, Shahin A, Patel M, Galadari S. Biochem Biophys Res Commun. 2009 Jun 12;383(4):426-32.  
Regulatory T cells and ST2 signaling control diabetes induction with multiple low doses of streptozotocin. Zdravkovic N, Shahin A, Arsenijevic N, Lukic ML, Mensah-Brown EP. Mol Immunol. 2009 Nov;47(1):28-36.  
Galectin-3 deficiency reduces the severity of experimental autoimmune encephalomyelitis. Jiang HR, Al Rasebi Z, Mensah-Brown E, Shahin A, Xu D, Goodyear CS, Fukada SY, Liu FT, Liew FY, Lukic ML. J Immunol. 2009 Jan 15;182(2):1167-73.  
Induction of interferon-gamma by Taenia crassiceps glycans and Lewis sugars in naive BALB/c spleen and peritoneal exudate cells. Dissanayake S, Shahin A. Mol Immunol. 2007 Mar;44(7):1623-30.  
IL-23 leads to diabetes induction after subdiabetogenic treatment with multiple low doses of streptozotocin. Mensah-Brown EP, Shahin A, Al-Shamisi M, Wei X, Lukic ML. Eur J Immunol. 2006 Jan;36(1):216-23.  
Adjuvant effect of Taenia crassiceps glycans against leishmanial antigens in mice infected with Leishmania mexicana. Dissanayake S, Shahin A, Ameen AM. Mol Immunol. 2005 Aug;42(12):1495-502  
Taenia crassiceps carbohydrates stimulate IL-6 expression in na´ve murine macrophages via Toll-like receptors (TLRs). Dissanayake S, Amith RS, Shahin A. Mol Immunol. 2004 Jun;41(4):391-8.  
Lack of the mediators of innate immunity attenuate the development of autoimmune diabetes in mice. Lukic ML, Mensah-Brown E, Wei X, Shahin A, Liew FY. J Autoimmun. 2003 Nov;21(3):239-46.  
Induction of immunoglobulin G1, interleukin-6 and interleukin-10 by Taenia crassiceps metacestode carbohydrates. Dissanayake S, Khan N, Shahin A, Wijesinghe S, Lukic M. Immunology. 2002 Dec;107(4):411-9.  
Lack of apoptosis of infiltrating cells as the mechanism of high susceptibility to EAE in DA rats. Lukic ML, Mensah-Brown E, Galadari S, Shahin A. Dev Immunol. 2001;8(3-4):193-200.  
Effector mechanisms in low-dose streptozotocin-induced diabetes. Lukić ML, Stosić-Grujicić S, Shahin A. Dev Immunol. 1998;6(1-2):119-28